How sleep impacts mental health (and vice versa)

March 25, 2025

We’ve all had one—a sleepless night that leaves you groggy and short-tempered, where even grabbing your morning coffee feels like a monumental effort. It’s no coincidence—poor sleep and mental health go hand in hand, often more than we realize.

Research shows that nearly 90% of people with depression report trouble falling or staying asleep. When you’re running on empty from a lack of sleep, it’s harder to handle stress or stay composed. Even simple moments can feel overwhelming, leaving you less equipped to deal with life’s curveballs. In other words, if your mental health feels off, your sleep might be sounding the alarm.

Sleep problems are often both a symptom and a cause of mental health challenges. Anxiety, stress, and depression can disrupt your ability to sleep, while chronic sleep deprivation makes these conditions worse—a vicious cycle that’s hard to break without targeted support.

So, how exactly are sleep and mental health connected? We’ll unpack the science behind this relationship and explore what steps you can take to feel more rested, clear-headed, and resilient.

How sleep health affects your mental health

Think of sleep as a nightly reset for your brain—a chance to recover and rebuild. Without it, both your mind and body struggle to keep up. Here’s what happens:

Emotional Regulation: Sleep helps reset the brain’s emotional centre, calming your responses to stress. Sleep deprivation, on the other hand, triggers heightened activity in the amygdala—the part of your brain responsible for processing emotions and stress—making minor challenges feel like mountains. This explains why small irritations suddenly feel overwhelming after a poor night’s sleep.

Cognitive Function: A restless night clouds your memory, weakens focus, and slows reaction times. Research from the National Institutes of Health shows that sleep deprivation impairs the brain’s prefrontal cortex, the area responsible for decision-making and emotional control. Over time, this cognitive “fog” can worsen symptoms of anxiety and depression, perpetuating a cycle that’s challenging to break.

Neurotransmitter Balance: Your brain relies on a group of chemical messengers called neurotransmitters—like serotonin, dopamine, and GABA—to help regulate mood and emotions. Serotonin supports feelings of calm and contentment, dopamine boosts motivation and pleasure, and GABA acts like a brake, helping your brain relax. When you don’t get enough sleep, these chemicals fall out of balance, leaving you irritable, sad, and mentally drained. This disruption can also make it harder to feel joy, focus, or stay motivated, which is why quality sleep is so crucial for emotional well-being. 

Brain Detoxification: During deep sleep, your brain clears out waste products, including beta-amyloid—a protein that, when it accumulates, is linked to cognitive decline and Alzheimer’s disease.

Without sufficient rest, these waste products build up, impairing brain function and potentially increasing the risk of long-term mental health and neurological issues. 

Running on little to no sleep chips away at your mental and physical resilience over time. Over time, sleepless nights build up, leaving you less resilient and more vulnerable to the challenges mental health struggles bring. 

How mental health disrupts sleep

Sleep and mental health share a symbiotic relationship—as one deteriorates, the other tends to follow, creating a cycle that’s hard to break. Anxiety, depression, stress, and trauma each play their part in disrupting sleep—and often in ways we don’t immediately recognize. 

Take anxiety, for example: a racing mind, tension in your body, and a constant sense of being on edge can keep you lying awake long after you’ve turned out the lights. Research from Harvard Medical School confirms that anxiety disorders are one of the most common contributors to chronic sleep issues, like insomnia.

For some, depression leads to oversleeping and grogginess; for others, it means restless nights. Studies show that while over 90% of people with depression report trouble sleeping, clinical sleep studies confirm that about 75% experience measurable sleep disturbances. Over time, this lack of rest drains energy, deepens feelings of sadness, and makes it harder to cope with daily life.

Finally, there’s trauma and PTSD. For those dealing with past traumatic experiences, nightmares, flashbacks, and hypervigilance make restful sleep incredibly difficult. Over time, this lack of quality sleep can worsen mental health and make healing feel out of reach.

It’s a frustrating cycle—poor sleep makes mental health symptoms worse, and those symptoms, in turn, make restful sleep harder to achieve. But here’s the good news: this cycle can be broken with the right tools and support.

Steps you can take right now

While persistent sleep problems may require professional support, here are practical steps you can take today:

Track Your Sleep and Mood: Start a journal to log how well you’re sleeping and how you feel during the day. Patterns will emerge—whether it’s anxious thoughts keeping you awake or stress building in the evenings. Identifying triggers is the first step to addressing them.

Create an Intentional Wind-Down Routine: Don’t wait for sleep to happen on its own. Try guided breathing exercises, gentle stretching, or meditation before bed to signal to your body that it’s time to relax. Free apps like Headspace or Calm can help you get started.

Limit Stimulants and Screens: Caffeine, nicotine, and intense light exposure can interfere with sleep quality. Aim to avoid stimulants in the afternoon and shut off screens at least an hour before bed.

Get Some Morning Light: Natural daylight in the morning helps regulate your circadian rhythm—your body’s internal clock that regulates sleep and wakefulness—making it easier to fall asleep at night. Even 15 minutes outdoors can make a difference—a simple but powerful change.

Exercise During the Day: Intense physical activity can directly lead to an increase in deep, restorative sleep. Aim for 20-30 minutes of movement earlier in the day to reap sleep benefits at night.

Small changes add up. By being proactive, you can improve your sleep—and your mental health—one step at a time.

When it's time to seek professional help

If these signs sound familiar, it might be time to consult a sleep professional:

Difficulty sleeping at least 3 nights a week for 3+ months (This is the clinical definition, but you don’t have to wait that long!)

Daytime exhaustion that impacts your work performance, relationships, or overall well-being.

Worsening anxiety, mood swings, or depression linked to poor sleep.

Snoring or gasping for breath during the night, which may indicate sleep apnea.

Conditions like insomnia, sleep apnea, or circadian rhythm disorders often require tailored treatment plans to address the root causes. Professional therapies, such as Cognitive Behavioral Therapy for Insomnia (CBT-I), can help retrain your brain to achieve natural, restful sleep without reliance on medication.

Take back control of your sleep and mental health

When sleep feels elusive and your mental health suffers, it’s easy to feel stuck. But it doesn’t have to be this way. While sleep and mental health are closely linked, improving sleep can make it easier to manage stress, anxiety, and depression. That’s why we focus on helping you sleep better first—so you can feel better overall.

At Careica Health, we specialize in treating sleep issues at the source. Our Insomnia Therapy Program is grounded in CBT-I, the leading treatment for chronic insomnia. It’s designed to help you retrain your sleep patterns and break the cycle of restless nights—without relying on sleep aids. Whether you’re struggling with insomnia or sleep apnea, we’re here to help.

Sign up for Insomnia Therapy or book a free discovery call to get started.

Have questions? Give us a call at 1-888-297-7889—we’re here to help.